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The George Institute for Global Health
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    We are on a mission to improve global health. Through rigorous, high-quality research, we’re striving to achieve meaningful and lasting change on a local and global scale. 
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    Our research finds solutions to some of the world’s biggest health challenges in critical areas including women’s health, planetary health, and food policy. Within each program, individual projects target specific challenges, providing local solutions to improve global outcomes.   
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Designing and operationalising trials

The George Institute has a highly skilled team which works to conceptualise, develop, and deliver innovative and impactful clinical trials, characterised by the following features: Reducing trial ‘waste’ Ensuring that clinical trials are efficient is crucial to minimising research ‘waste’, which most commonly results from the costs associated with poorly conceived research questions, inappropriate study design, failure to adequately report on all areas being analysed, and inefficient operational conduct. Trial efficiency can be improved via two key mechanisms- by design and by conduct. Trial design involves the development and application of innovative statistical methods including adaptive and pragmatic designs. The first involves adapting some elements of the design as the trial progresses (rather than waiting for the trial to end). A pragmatic trial evaluates a health intervention in a setting as close as possible to real-world conditions. Adaptive designs help to gener

What are clinical and community trials

What are clinical trials? Clinical trials are research studies with humans, designed to test new treatments to find better ways to prevent, detect or treat disease1. Clinical trials are also sometimes referred to as interventional trials. The sorts of treatments being investigated include medicines or drugs, cells and other biological products, surgical procedures, radiologic procedures, devices, behavioural treatments, process-of-care changes, preventive care, and other items.2 Clinical trials rely on having members of the general public agree to take part. What happens in a clinical trial? In a clinical trial, participants meet with researchers who go through what the clinical trial will involve. All participants must be advised about the objectives of the research, what is expected of them, as well as any risks that may be experienced during and after the trial. Trials must follow a carefully controlled protocol, which is a plan that describes what researchers will do in the stu

Innovative clinical trials

Researchers at The George Institute for Global Health, UK, led by Executive Director Professor Otavio Berwanger, are spearheading a programme of work to transform that way we deliver large-scale clinical trials. This programme is borne out of a recognition of the limitations of the ‘traditional’ clinical trial model – and the health gains (social, environmental and economic) – to be had in investigating pragmatic, innovative and efficient approaches. In both the so-called ‘traditional’ and innovative trial models, the gold standard of randomisation controls for both known and unknown confounding factors that could influence trials outcomes, and represents the optimal method to work out whether a healthcare intervention reduces the risk of patient-important outcomes and so inform clinical practice. Where the two models differ is that the traditional approach requires participants be screened and recruited in a trial site by a team of investigators, and so demands both a

Cost and access: the barriers stopping Aboriginal men getting prostate cancer surgery

News / Media release 05 Aug 2026

Veronica Le Nevez

Profile

Veronica Le Nevez is Co-Director, Impact and Engagement Australia at The George Institute for Global Health, where she leads the Institute’s advocacy and policy engagement activities in Australia and the Pacific region to help increase the impact of the institute’s health and medical research. Programmes of activity include preventive health, food and nutrition, primary care, injury, better treatments for non-communicable diseases, women’s health and critical care, and others.

Veronica has spent her career in public policy, having worked extensively in the environment portfolio and in digital innovation. Prior to joining The George Institute, Veronica was General Manager Policy and Advocacy at the Royal Australasian College of Physicians, and held policy development and implementation roles at the University of Sydney. Veronica has a Bachelor of Science in Resource and Environmental Management, and a Master of Environmental Science from Macquarie University and is currently studying a Masters of Business Administration at the University of New South Wales.

Anna Palagyi

Profile

Dr Anna Palagyi is a health systems scientist with expertise in co-design methodology and implementation studies with mixed-methods evaluation. She holds positions as Program Lead - Ageing & Health Systems in the Centre for Health Systems Science at The George Institute for Global Health and Conjoint Associate Professor at UNSW Sydney.

Anna's research centres on the co-design of effective implementation strategies to strengthen primary health care services in resource-constrained settings of the Asia-Pacific region. She has a particular interest in the development of appropriate health system responses to population ageing: Anna previously implemented a national longitudinal study on aspects of healthy ageing in older Australians with cataract, and currently collaborates with governments, civil society organisations and academic institutions across several Pacific Island countries to identify national healthy ageing policy, program and service priorities.

Anna is committed to evidence-informed health policy and practice. She has a strong track record of partnering with government stakeholders in the design and implementation of policy-relevant research, has co-authored commissioned reports for government bodies and advocacy groups, and has produced policy briefs for government departments.

Chhavi Bhandari

Profile

Chhavi Bhandari is Co-Director, Impact & Engagement at The George Institute for Global Health, where she leads a global programme of advocacy and stakeholder engagement to maximise the impact of our health and medical research. Her work focuses on multilateral partnerships and advancing community engagement and involvement.  She also serves as Community Engagement and Involvement Lead for the NIHR Global Health Research Centre on NCDs and Environmental Change, co-chairs the WHO NCD Lab on Women and Girls, and contributes to global health policy through WHO civil society groups. With an MBA and international healthcare experience across India, the UK, Australia, and beyond, Chhavi brings a globally informed yet locally grounded approach to advancing equitable health systems.

The George Institute leading the Psychosocial Support for Front Line health Workers (FLWs)

News 04 May 2022

Winners of The George Institute and UNICEF India Innovation Challenge

News 05 Oct 2021

Meet our Finalists of the Covid-Care@Home Innovation Challenge

News 02 Aug 2021

Reconnections: Research, Community and Enablement in Building Health Worker Wellbeing

Event 20 May 2026 3:30 PM IST

Stress levels of frontline healthcare workers assessed at unique workshop organised by The George Institute & UNICEF

News 02 Sep 2021

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The George Institute for Global Health

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    Acknowledgement of country

    The George Institute acknowledges First Peoples and the Traditional Custodians of the many lands upon which we live and work. We pay our respects to Elders past and present, and thank them for ongoing custodianship of waters, lands and skies.

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    The George Institute for Global Health is proud to work in partnership with UNSW Sydney, Imperial College London and the Manipal Academy of Higher Education, India.

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    The George Institute for Global Health is a registered charity. ABN 90 085 953 331

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