Background:Globally, nearly 9 million injuries and ~180,000 deaths occur annually due to burns, with the majority occurring in low-and middle-income countries. Almost two-thirds of burn injuries occur in Africa and South-East Asia. Young children are disproportionally affected with under 5-year-olds in the African region having an incidence of burn deaths of over double the global rate. Burn injuries are particularly problematic in urban slum communities such as Kisenyi, where our recent work revealed an extremely high incidence (32%) of burns in children under the age of 5.Current first aid responses frequently involve home remedies such as applying cooking oil and sugar, eggs and other food materials, commercial creams, toothpaste, soap and traditional medicines including mixtures of urine, mud and cow dung. Yet best practice involves simply cooling the burn with water. Additionally, research shows carers are often reluctant to seek formal medical care – a key factor in poor outcomes for children with bur

Background There is a long-standing assumption that medicine, and the research underpinning medical interventions, is sex and gender neutral, however there is a growing body of evidence describing sex and gender differences in disease prevention, diagnosis, treatment and health outcomes. Despite this, much research continues to be done without taking sex and gender into account, leading to gaps in the evidence base informing our health care policy and practice Aims To address gaps in the collection, analysis and reporting of sex and gender in health and medical research in Australia. To build capacity among researchers, scientists and clinicians, and drive change in this area Method The project involves three phases: Surveys, interviews, web-based searches; Development and evaluation of policy frameworks and training materials; and Health economic analysis. Potential Impact Each stakeholder within the health and medical research sector in Australia encourages

BackgroundDementia is a decline in thinking skills that affects our ability to conduct day-to-day activities. It is not a normal part of ageing however there is a greater risk of dementia as we age. There are currently around 472,000 people affected by dementia in Australia, which is predicted to double in the next 35 years.Studies have shown that high blood pressure increases the risk of dementia. Some studies suggest that medication to lower blood pressure might help reduce the risk of dementia but there is insufficient evidence for clear recommendations. The RECALL-Pilot trial aims to address this gap in the current body of research.AimTo encourage nationwide participation, RECALL-Pilot is trialling a new online approach to clinical trials, which will inform the future design of a larger clinical trial on dementia risk reduction.Research MethodologyThere are no face-to-face appointments in this study except for two blood tests – participants will carry out the rest of the pilot trial online from home.&nb

BackgroundHousing is a social and cultural determinant of health and wellbeing. Housing conditions, housing security and surrounding home environments all impact on people’s health and wellbeing. Aboriginal and Torres Strait Islander people’s wellbeing is supported by housing that meets their physical, social, emotional, cultural and locational needs. Living on Country and close to family and community support, as well as services, are critical factors in supporting wellbeing.Aboriginal and Torres Strait Islander social housing tenants in urban Sydney are often faced with the experience of living in housing that does not meet their physical, social, emotional, cultural and locational needs. The meanings of home and desired outcomes of tenants are not necessarily known, understood or considered by social housing providers. Additionally, the social housing system is difficult to navigate in instances when tenants wish to address their housing needs, for example, requesting a repair or requesting a transfer

Background Pregnant women, particularly those in low- and middle-income countries, are among the most vulnerable populations to climate change. India has experienced a marked rise in the intensity, frequency, and duration of heatwaves over the last half-century, with 2022 and 2024 being the hottest years since 1901. Extreme heat exposure has been linked to several adverse pregnancy outcomes, including: Preterm birth Stillbirth Gestational diabetes Small for gestational age babies Preeclampsia However, the biological mechanisms linking environmental heat to these outcomes remain poorly understood. Aim The Heat in Pregnancy – India (HiP-India) project is a multi-partner coalition of researchers across India and the UK seeking to understand why exposure to extreme heat leads to adverse birth outcomes. This Wellcome Trust-awarded project is a collaborative effort between the Translational Health Science and Technology Institute (THSTI),