About this study Individuals receiving dialysis are at risk of heart failure and heart-related death. There is an urgent need for treatments that reduce the risk of these problems in patients that require dialysis. Spironolactone is a medication used to prevent heart failure and related deaths in patients that do not require dialysis. It works by blocking a hormone (aldosterone) in your body that causes high blood pressure and can damage the heart. Although spironolactone is very effective in patients that do not require dialysis, we do not know if spironolactone is effective in dialysis patients. Our research will help determine if spironolactone reduces heart failure and heart related deaths in dialysis patients. Eligibility criteria Inclusion Age ≥45 years or ≥18 with a history of diabetes On dialysis ≥ 90 days On either Haemodialysis prescribed at least 2 treatments per week or Peritoneal dialysis prescribed with at least 1 exc

About the study Chronic Obstructive Pulmonary Disease (COPD) is the third-leading cause of global health-related disease and deaths. Heart disease is very common in people diagnosed with COPD and is often the cause of health-related sickness and hospitalisations, causing 30 – 50% of deaths. Studies repeatedly show that heart disease is often not diagnosed in persons with COPD, and when it is diagnosed it is often under-treated. People with COPD are also commonly not included in clinical trials of drugs which treat heart disease and heart-related deaths. Beta (β)-blockers are medications often used to treat heart disease. In this study, we will be investigating whether pro-active treatment with a β-blocker in people with COPD can reduce heart-related events, such as strokes and heart attacks. This is important for people with COPD with either known or unknown underlying heart disease. The study also aims to investigate whether this treatment influences number of respiratory flare ups (exace

About this study Australians are increasingly shopping online for their groceries however we don’t have much evidence on the level of influence of information available to consumers online. The aim of this research is to understand how online grocery purchasing choices may change depending on the information being presented online. Recruitment criteria Aged 18-75 Have high blood pressure Diagnosed by your doctor or currently taking a stable dose of blood pressure lowering medications Regularly purchase most of their groceries online from Woolworths and plan to continue for the duration of the study (4 months) or for those who don’t currently shop with Woolworths, you will also be eligible if you switch to shopping at Woolworths for the duration of the study Would be willing to shop for their groceries online for the study What’s involved? Participants will be asked to complete the following research activities if they consent to join t