Kate has a background in Pharmacology and a PhD in the inflammatory system. She began her employment at TGI in March 2018, mainly working within the renal and metabolic division. Kate’s clinical research operations skills developed whilst working on the REDUCCTION study where she managed sites, coordinated event adjudication processes, maintained data trackers, monitored data collection, upheld ethics and research governance approvals, submitted ethics amendments, coordinated site payments, and maintained close communication with participating study sites. Her expertise has also been lent to other studies including TRIDENT (project forecasting and coordinating outcome adjudications), TRACK (unblinded team member), RESOLVE (event verification), and ATHENA (UAT). Experience has also been obtained in start-up, site initiation, site close-out, protocol and other document development, and exposure to data linkage processes.

Kate currently manages the PERFORM-AKI, ACCESS HD, DISCOVER and REVERSE studies.

It is with great sadness that we share the news that Margie passed away in January 2026. Her vibrant and wide-reaching legacy continues, not least in the work to which she dedicated much of her life: on how to prevent unintentional injuries, particularly in resource-strapped countries.

While road injuries were the biggest issue, Margie's work also canvased other significant problems of drowning, burns and falls, and identified interventions that could save lives. Her research looked at what works, specifically in developing countries. It provided evidence on how to prevent injuries before they happen. But it also looked at the post-crash phase, working with nurses – who are the mainstay of healthcare provision in developing countries – to provide optimum treatment management. In some developing countries, traumatic injuries account for up to 70%-80% of the caseloads in emergency rooms. If you can stop these injuries upstream, there are enormous gains for healthcare systems, both financially and in terms of workforce needs.

Representing The George Institute for Global Health and South Africa, Margie was a member of the Commonwealth Road Safety Initiative Expert Panel and together with colleagues from Kenya and Canada led the data analysis for the reports being developed ahead of the 3rd Ministerial level meeting in Sweden in February 2020 and the CHOG meeting in Rwanda. She was also a member of the Academic Expert Group for this Ministerial meeting, a group responsible for making an independent and scientific assessment of the progress made during the Decade of Action for Road Safety. The Academic Expert Group will also recommend a road safety strategy for the period 2020-2030. Margie was also Chair of the Global Advisory Board for the Malawi Road Safety Research and Implementation Unit at the University of Malawi.

Dennis Mazingi is a medical doctor and general surgeon with a special interest in paediatric injury prevention, global surgery, and surgically correctable NCDs. He has worked in clinical medicine and surgery in southern Africa for almost a decade and is currently pursuing a DPhil in the University of Oxford’s Nuffield Department of Surgical Sciences in the global surgery group.

His work focuses on trauma surveillance and quality improvement in paediatric trauma care in Zimbabwe. He is ably supervised by Professor Kokila Lakhoo and Professor Ashok Handa at the Nuffield Department of Surgical Sciences and Professor Godfrey Muguti at the University of Zimbabwe.

Prior to joining The George Institute Dennis obtained his undergraduate medical degree at the University of Malawi, College of Medicine and an MMed (Master’s in Medicine) in General Surgery at the University of Zimbabwe, College of Health Sciences. He holds a first-class degree in International Health and Tropical Medicine (IHTM) from the University of Oxford and is a fellow of the College of Surgeons of South Africa as well as a Beit Trust Scholar.

He has worked in various research collaboratives in the field of global surgery, paediatric surgery, and general surgery. Dennis’s other interests lie in clinical surgery, surgical education, disruptive health technologies, frugal innovations, health systems and implementation research.

Dennis wants to see a healthier, more prosperous, more equitable world through surgical care and research. His mission is to help accelerate progress towards SDG target 3.6: to halve the number of deaths and injuries from road traffic accidents by 2030 in Zimbabwe and globally; and to scale up quality surgical and anaesthesia care to the 5 billion people who need it through 2030 and beyond.