Xiaoying Chen

About Xiaoying Chen

Senior Research Fellow, Brain Health Program

  • PhD,
  • BPharm,
  • BMgt

Dr Xiaoying Chen is a Heart Foundation Postdoctoral Fellow and a Senior Research Fellow in the Global Brain Health Program at the George Institute for Global Health. She leads the stroke and technology themes in the Brain Health Program at the George Institute. She has over 19 years’ experience in international multicenter clinical trials and 15 years in designing and conducting large international clinical trials. She has led and been pivotal to the success of multiple international randomised controlled trials which have had significant impact on guidelines, and decision-making in clinical practice. Her research program focuses on treatment in acute stroke care and stroke recovery by designing and implementing innovative large international clinical trials, developing new tools and measures to support stroke care, especially for remote and underserved population.

Dr Chen is an early career researcher in Clinical trials and stroke. She has vast experience in large scale stroke trials and has been pivotal to the success of multiple world-class large international clinical trials, including as one of the Lead PIs of A multi-faCtorial, mulTi-arm, multi-staGe, randomised, gLOBal Adaptive pLatform trial for stroke (ACT-GLOBAL) aiming to be executed through 300+ hospitals in 20+ countries, Global Project Lead of landmark trial - The third, INTEnsive care bundle with blood pressure Reduction in Acute Cerebral haemorrhage Trial (INTERACT3) with 7000+ stroke patients enrolled from 120+ centres from 10 countries, Senior Project Lead of INTEnsive blood pressure Reduction in hyperacute Cerebral haemorrhage Trial (INTERACT4) with 2200+ stroke patients enrolled from 50+ centres in China, Senior Project Lead of Second Enhanced Control of Hypertension and Thrombectomy Stroke Study (ENCHANTED2) with 800+ stroke patients enrolled from 50+ centres in China, Global Project Lead of other large international clinical trials, including ENCHANTED, INTERACT2 and SAVE.

Title: Relative Reductions in Systolic Blood Pressure and Functional Outcomes in Intracerebral Hemorrhage: A pooled analysis of four INTERACT and ATACH-2 individual participant data

International Journal of Stroke Date published:

Systolic Blood Pressure Trajectory and Outcomes in Acute Intracerebral Hemorrhage

Neurology Date published:

Cumulative blood pressure and risk of dementia and cognitive decline: a systematic review and meta-analysis

The Journal of Prevention of Alzheimer's Disease Date published:

Effects of Blood Pressure Lowering Across Hematoma Volume in Acute Intracerebral Hemorrhage: Pooled Analysis of the Four INTERACT and ATACH -2 Trials

Annals of Neurology Date published:

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