The George Institute has a highly skilled team which works to conceptualise, develop, and deliver innovative and impactful clinical trials, characterised by the following features: Reducing trial ‘waste’ Ensuring that clinical trials are efficient is crucial to minimising research ‘waste’, which most commonly results from the costs associated with poorly conceived research questions, inappropriate study design, failure to adequately report on all areas being analysed, and inefficient operational conduct. Trial efficiency can be improved via two key mechanisms- by design and by conduct. Trial design involves the development and application of innovative statistical methods including adaptive and pragmatic designs. The first involves adapting some elements of the design as the trial progresses (rather than waiting for the trial to end). A pragmatic trial evaluates a health intervention in a setting as close as possible to real-world conditions. Adaptive designs help to gener

The health of women and girls, people with variations in sex characteristics (intersex people) and trans and gender-diverse people has been understudied in health and medical research. An almost exclusive focus on male cells, male animals and men in health and medical research has led to poorer health outcomes and evidence gaps for women, intersex people, and trans and gender-diverse people, and inefficient health spending. Women’s health research often focuses only on their sexual, reproductive, and maternal health rather than the leading causes of death and disability for women. Research on intersex and gender-diverse people is even less developed and availability of health data remains a challenge. For some health conditions, we also have very little information on men and boys, given the conditions occur predominantly in women. The Centre for Sex and Gender Equity in Health and Medicine is addressing these inequities through world-class research, advocacy for policy change, and capacity building

The purpose of FoodSwitch is to bring transparency to the world’s food supply with a vision of an optimised food system for human health and the health of our planet. There are many studies highlighting the link between diet, ill-health and disease. Globally, 1 in 5 deaths are associated with poor diet, with cardiovascular disease being the biggest contributor, followed by cancers and type 2 diabetes. In addition, it is estimated that between 30% and 40% of anthropogenic greenhouse gas emissions (GHGe) are attributable to the global food system. To achieve our purpose, we collect and analyse information from packaged food labels to generate data and insights that can influence government policy and industry practice toward improved food environments. Additionally, we have several apps that allow consumers to make better food choices: Our FoodSwitch App provides simple health and nutrition information on a scanned product and suggests healthier alternatives to 'switch' to, and