Globally, road traffic collisions are the leading cause of death among adolescents. India has an increasing burden of road injuries among adolescents. Our previous qualitative work found that understanding context is critical to enable implementation of effective interventions to reduce the burden of road injury among adolescents. On 29th July 2020, the New Education Policy was introduced by the Government of India which proposes accessible education for special groups by providing bicycles. Knowing the vulnerability of pedestrians and cyclists, we need measures to ensure equitable and safe routes to school, to achieve the goal of accessible education for every child. We will use a sequential, mixed methods approach to evaluate the road environment quantitatively using the International Road Assessment Programme (iRAP) Star Rating for School App, followed by qualitative investigation with key stakeholders to assess system capacity for implementation of safe school routes in Madhya Pradesh. The proposed met

The aim of the project is to promote China-Australia co-operation in HTA through knowledge exchange and research collaboration

BackgroundImmunoglobulin A Nephropathy (IgAN) is the most common type of kidney inflammation worldwide and a leading cause of kidney failure, often requiring dialysis or transplant. • The TESTING trial showed that significant kidney problems like kidney failure or a major decline in kidney function often start appearing two-to-three years after starting treatment. A post-trial observation study is a crucial and efficient way to answer key questions about whether the benefits of steroids continue over time and if lower steroid doses provide similar long-term benefits safely for kidney health.AimsTo follow TESTING study participants for a longer period to see if taking methylprednisolone for six to nine months leads to lasting benefits in preventing end-stage kidney failure. To resolve persisting uncertainties regarding the use and long-term benefits of corticosteroids as a therapy for IgA nephropathy.MethodsTESTING-ON is a post-trial observational study of participants randomised into the TEST

BackgroundThe World Health Organization (WHO) has identified climate change as the greatest threat to human health in the twenty-first century, with an estimated 250,000 additional deaths per year between 2030 and 2050 due to malnutrition, malaria, diarrhoea, and heat stress alone. Climate change is contributing to increase adverse impact not restricted to human health, but also extending to social, economic, and political domains.It is widely recognised that identifying practical solutions to handle the health aspects of climate change needs trans- and multi-disciplinary research. As the window for effective responses is rapidly closing, identifying priority research questions on climate change is key from the point of both resourcing and action for funders and academics.AimsTo identify priority research questions on climate change and health in India in the following domains:Impact of climate change on health and diseaseInterventions to protect health from climate changeClimate change adaptation and mitigat

BackgroundAnemia is a serious public health issue in India with one of the highest prevalence among women of reproductive age (18-49 years) globally. Despite the targeted and concerted efforts, anemia has shown an increasing trend over the past decade. Tripura, one among the Northeastern states of India, has the highest prevalence of WRA in the region at 67.2%. To address this crisis, our research aims to identify the contextual factors affecting anemia in different population groups in Tripura and implement multi-sectoral intervention to address anemia in women of reproductive age group.AimAssess the contextual factors affecting anemia in women of reproductive age (18-49 years) of different population groups (tribal/non-tribal) in Tripura.Co-develop and implement a multisectoral intervention to reduce anemia among women of reproductive age.Research MethodologyA quasi-experimental study design with a mixed method approach is employed. The study will be conducted in four phases -- Formative; Intervention desig

BackgroundSpontaneous intracerebral haemorrhage (ICH) accounts for approximately 10-15% of all strokes but stands for 50% of stroke-related morbidity and mortality. Approximately half of all patients with ICH have a decreased level of consciousness at hospital admission. For many years, randomized clinical trial (RCTs) have failed to establish a specific beneficial treatment after ICH. A study conducted in low- and middle-income countries has demonstrated a beneficial effect of a treatment package consisting of early intensive blood pressure lowering, as well as the treatment of pyrexia and elevated blood glucose levels. The I-CATCHER team is now planning to extend the study in Sweden and Australia, as well as to other high-income countries. AimThis study aims to investigate whether a structured treatment package (Care Bundle) improves 6-month prognosis in patients with spontaneous ICH compared to standard care. Research MethodologyI-CATCHER is an international, multicentre, batc