SuSTAInX - Supporting Successful Transition to Adult belts In Cars: examining effectiveness of eXisting tools
Background Optimal crash protection requires the most appropriate restraint for a child’s size. For children ≥7 years of age, parents can choose whether they use seat belts or a booster seat. However, there is confusion about when children can safely use seat belts. The result is that many children >7 years inappropriately use seat belts, increasing risk of injury in a crash. There is existing information and advice aimed at helping parents to decide whether it is safe for their child to use an adult seat belt, however, they have not been tested for effectiveness.
Aims The overall aim of this study is to explore the information that parents need in order to make safe and correct decisions when it comes to restraining children using adult seat belts while travelling in a car. The data that we collect from this study will help us to develop easy-to-understand information resources and materials to support parents and help to reduce the level of incorrect use of adult seat belts
Comparing dialysis treatments for end-stage kidney disease (CONVINCE trial)
One in ten people worldwide have chronic kidney disease. Some of them progress to end-stage kidney disease (ESKD), which is when their kidney function falls below around 10% of normal. ESKD cannot be cured and people with the condition require either a kidney transplant or lifelong treatment with dialysis. Currently, haemodialysis is the most common form of dialysis used in the treatment of ESKD. However, it is not good at removing larger waste molecules from the blood and is often associated with a poor quality of life.
A large international multi-centre clinical trial (CONVINCE) investigated the superiority of an alternative dialysis treatment, haemodiafiltration, as compared to haemodialysis. Haemodiafiltration more effectively removes larger molecules that are accumulated, and was hypothesised to have better outcomes in terms of mortality, cardiovascular events, and quality of life.
The research team sought to determine the best treatment by conducting an international trial involving 1,36
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