BackgroundImmunoglobulin A Nephropathy (IgAN) is the most common type of kidney inflammation worldwide and a leading cause of kidney failure, often requiring dialysis or transplant. • The TESTING trial showed that significant kidney problems like kidney failure or a major decline in kidney function often start appearing two-to-three years after starting treatment. A post-trial observation study is a crucial and efficient way to answer key questions about whether the benefits of steroids continue over time and if lower steroid doses provide similar long-term benefits safely for kidney health.AimsTo follow TESTING study participants for a longer period to see if taking methylprednisolone for six to nine months leads to lasting benefits in preventing end-stage kidney failure. To resolve persisting uncertainties regarding the use and long-term benefits of corticosteroids as a therapy for IgA nephropathy.MethodsTESTING-ON is a post-trial observational study of participants randomised into the TEST

BackgroundThe World Health Organization (WHO) has identified climate change as the greatest threat to human health in the twenty-first century, with an estimated 250,000 additional deaths per year between 2030 and 2050 due to malnutrition, malaria, diarrhoea, and heat stress alone. Climate change is contributing to increase adverse impact not restricted to human health, but also extending to social, economic, and political domains.It is widely recognised that identifying practical solutions to handle the health aspects of climate change needs trans- and multi-disciplinary research. As the window for effective responses is rapidly closing, identifying priority research questions on climate change is key from the point of both resourcing and action for funders and academics.AimsTo identify priority research questions on climate change and health in India in the following domains:Impact of climate change on health and diseaseInterventions to protect health from climate changeClimate change adaptation and mitigat

BackgroundAnemia is a serious public health issue in India with one of the highest prevalence among women of reproductive age (18-49 years) globally. Despite the targeted and concerted efforts, anemia has shown an increasing trend over the past decade. Tripura, one among the Northeastern states of India, has the highest prevalence of WRA in the region at 67.2%. To address this crisis, our research aims to identify the contextual factors affecting anemia in different population groups in Tripura and implement multi-sectoral intervention to address anemia in women of reproductive age group.AimAssess the contextual factors affecting anemia in women of reproductive age (18-49 years) of different population groups (tribal/non-tribal) in Tripura.Co-develop and implement a multisectoral intervention to reduce anemia among women of reproductive age.Research MethodologyA quasi-experimental study design with a mixed method approach is employed. The study will be conducted in four phases -- Formative; Intervention desig

BackgroundMany older people experience difficulties achieving good seatbelt fitment and comfort in vehicles. The use of comfort accessories like cushions and pads is relatively common among older people travelling in vehicles. Research has shown that some of these accessories can have a detrimental effect on safety in a crash. Medical practitioners, allied health and road safety professionals are ideally placed to provide advice to older people about how to redress these issues and how to safely achieve comfort in vehicles. The ‘Vehicle Safety for Older Drivers’ project was initiated to develop evidence-based guidelines for tailoring advice about safe and comfortable travel in vehicles as a tool for use by these practitioners. Older people also need to be able to access guidance about comfort and safety in vehicles although may not need the same level of detail. For this reason, simple informative material targeting older people to raise awareness of safety issues in vehicles, and to allow for inform

BackgroundSpontaneous intracerebral haemorrhage (ICH) accounts for approximately 10-15% of all strokes but stands for 50% of stroke-related morbidity and mortality. Approximately half of all patients with ICH have a decreased level of consciousness at hospital admission. For many years, randomized clinical trial (RCTs) have failed to establish a specific beneficial treatment after ICH. A study conducted in low- and middle-income countries has demonstrated a beneficial effect of a treatment package consisting of early intensive blood pressure lowering, as well as the treatment of pyrexia and elevated blood glucose levels. The I-CATCHER team is now planning to extend the study in Sweden and Australia, as well as to other high-income countries. AimThis study aims to investigate whether a structured treatment package (Care Bundle) improves 6-month prognosis in patients with spontaneous ICH compared to standard care. Research MethodologyI-CATCHER is an international, multicentre, batc

GlutenSwitchGlutenSwitch helps people living with coeliac disease or a gluten intolerance to identify alternatives that are both gluten-free and similar in healthiness to the scanned item.We have recently launched a new standalone app called GlutenSwitch with added features to help people find foods that are both declared gluten-free by the manufacturer and also foods that we have estimated as gluten-free based on their ingredients. We have also introduced a new feature that allows the user to select the store they are in to show choices that are likely available in their location.The GlutenSwitch app is available in Australia:GlutenSwitch Australia - [Android] [iOS]  FAQsWhat is GlutenSwitch?GlutenSwitch will give you the gluten status of a product, based on if the product is declared gluten-free by the manufacturer or that we have estimated as gluten-free based on their ingredients. GlutenSwitch will also list similar foods that are declared gluten-free and estimated gluten free. You can access th

BackgroundHousing is a social and cultural determinant of health and wellbeing. Housing conditions, housing security and surrounding home environments all impact on people’s health and wellbeing. Aboriginal and Torres Strait Islander people’s wellbeing is supported by housing that meets their physical, social, emotional, cultural and locational needs. Living on Country and close to family and community support, as well as services, are critical factors in supporting wellbeing.Aboriginal and Torres Strait Islander social housing tenants in urban Sydney are often faced with the experience of living in housing that does not meet their physical, social, emotional, cultural and locational needs. The meanings of home and desired outcomes of tenants are not necessarily known, understood or considered by social housing providers. Additionally, the social housing system is difficult to navigate in instances when tenants wish to address their housing needs, for example, requesting a repair or requesting a transfer