TY - JOUR
AU - Kengne A.
AU - Dzudie A.
AU - Menanga A.
AU - Kingue S.
AU - Lekoubou A.
AU - Nkoke C.
AU - Jingi A.
AB - <p>
BACKGROUND: Rheumatic Heart Disease (RHD) remains a major cause of childhood acquired heart disease in developing countries. However reported echocardiographic features are limited to a few countries. This report is on the demographic and echocardiographic features of RHD in children using data from the largest referral hospital in Yaounde, the capital city of Cameroon. METHODS: The register of the cardiac ultrasound unit of the Yaounde General Hospital for the period 2003-2013 served as basis for data collection. RHD diagnosis was based on the World Heart Federation Criteria for the diagnosis of RHD. Demographic data, pattern of valve lesions and severity were analyzed. RESULTS: A total of 1130 first echocardiographic examinations were performed in children aged <!--= 18 years. Sixty-five (5.8 %) had a definite echocardiographic diagnosis of RHD with their mean age being 11.8 years (SD 3.6) and 31 (47.1 %) being boys. The commonest primary reasons for requesting an echocardiographic examination were a clinical diagnosis of RHD (24.6 %) without heart failure, a clinical diagnosis of heart failure (24.6 %), and heart murmurs (21.5 %). Isolated mitral regurgitation was the most common valve lesion (49.2 %) and was frequently associated with aortic regurgitation (35.4 %). Severe lesions were found in 63.3 % of participants. No right heart lesion was reported. CONCLUSIONS: A sizable proportion of children undergoing echocardiographic examination at this major referral hospital in Cameroon had RHD, with lesions found only on the left heart. These lesions predominated on the mitral valve, were commonly associated with aortic regurgitation, and more often severe.-->
</p>

AD - Department of Internal Medicine and Medical Specialties, University of Yaounde 1, Yaounde, Cameroon.<br/>Department of Neurosciences, Division of Neurology, Medical University of South Carolina, Charleston, SC, USA.<br/>Department of Internal Medicine, Douala General Hospital, Douala, Cameroon.<br/>Non-Communicable Diseases Research Unit, South African Medical Research Council, Cape Town, South Africa. apkengne@yahoo.com.<br/>Department of Medicine, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa. apkengne@yahoo.com.<br/>The George Institute for Global Health, University of Sydney, Sydney, Australia. apkengne@yahoo.com.
AN - 27000111
BT - BMC Pediatrics
C2 - PMC4800770
DP - NLM
ET - 2016/03/24
LA - eng
LB - AUS<br/>PROF<br/>FY16
M1 - 1
N1 - Nkoke, Clovis<br/>Lekoubou, Alain<br/>Dzudie, Anastase<br/>Jingi, Ahmadou Musa<br/>Kingue, Samuel<br/>Menanga, Alain<br/>Kengne, Andre Pascal<br/>England<br/>BMC Pediatr. 2016 Mar 21;16(1):43. doi: 10.1186/s12887-016-0584-z.
N2 - <p>
BACKGROUND: Rheumatic Heart Disease (RHD) remains a major cause of childhood acquired heart disease in developing countries. However reported echocardiographic features are limited to a few countries. This report is on the demographic and echocardiographic features of RHD in children using data from the largest referral hospital in Yaounde, the capital city of Cameroon. METHODS: The register of the cardiac ultrasound unit of the Yaounde General Hospital for the period 2003-2013 served as basis for data collection. RHD diagnosis was based on the World Heart Federation Criteria for the diagnosis of RHD. Demographic data, pattern of valve lesions and severity were analyzed. RESULTS: A total of 1130 first echocardiographic examinations were performed in children aged <!--= 18 years. Sixty-five (5.8 %) had a definite echocardiographic diagnosis of RHD with their mean age being 11.8 years (SD 3.6) and 31 (47.1 %) being boys. The commonest primary reasons for requesting an echocardiographic examination were a clinical diagnosis of RHD (24.6 %) without heart failure, a clinical diagnosis of heart failure (24.6 %), and heart murmurs (21.5 %). Isolated mitral regurgitation was the most common valve lesion (49.2 %) and was frequently associated with aortic regurgitation (35.4 %). Severe lesions were found in 63.3 % of participants. No right heart lesion was reported. CONCLUSIONS: A sizable proportion of children undergoing echocardiographic examination at this major referral hospital in Cameroon had RHD, with lesions found only on the left heart. These lesions predominated on the mitral valve, were commonly associated with aortic regurgitation, and more often severe.-->
</p>

PY - 2016
SN - 1471-2431 (Electronic)<br/>1471-2431 (Linking)
EP - 43
T2 - BMC Pediatrics
TI - Echocardiographic pattern of rheumatic valvular disease in a contemporary sub-Saharan African pediatric population: an audit of a major cardiac ultrasound unit in Yaounde, Cameroon
VL - 16
Y2 - FY16
ER -