01545nas a2200217 4500000000100000008004100001260001700042100001600059700001900075700001100094700001500105700001300120700001400133700001900147245008300166250001500249300001100264490000700275520099400282020005101276 2015 d c-456037184511 aCampbell N.1 aJohnson Claire1 aRaj T.1 aTrudeau L.1 aBacon S.1 aPadwal R.1 aWebster Jacqui00aThe science of salt: a systematic review of clinical salt studies 2013 to 2014 a2015/03/20 a401-110 v173 a

The authors provided a systematic review of the clinical and population health impact of increased dietary salt intake during 1 year. Randomized controlled trials or cohort studies or meta-analyses on the effect of sodium intake were examined from Medline searches between June 2013 to May 2014. Quality indicators were used to select studies that were relevant to clinical and public health. A total of 213 studies were reviewed, of which 11 (n=186,357) were eligible. These studies confirmed a causal relationship between increasing dietary salt and increased blood pressure and an association between several adverse health outcomes and increased dietary salt. A new association between salt intake and renal cell cancer was published. No study that met inclusion criteria found harm from lowering dietary salt. The findings of this systematic review are consistent with previous data relating increased dietary salt to increased blood pressure and adverse health outcomes.

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