@article{16560,
  author = {Wood A. and Raju P. and Pell J. and Chow Clara and Neal Bruce and Patel Anushka},
  title = {Prevention of cardiovascular disease in a rural region of India and strategies to address the unmet need},
  abstract = {<p>
OBJECTIVES: To determine levels of cardiovascular disease (CVD) prevention and to model the potential impact of improved prevention strategies for a large rural Indian region. DESIGN: A cross-sectional study with modelling of coronary heart disease (CHD) events over 10 years. SETTING: Rural Andhra Pradesh, India. PARTICIPANTS: A stratified random sample of 1,079 adults 30 years and older. MAIN OUTCOME MEASURES: Proportion on medical and behavioural treatments for prevention of CVD; estimated number of CHD events using a locally recalibrated Framingham risk equation. RESULTS: Among the 3.5% (95% CI 2.1% to 4.9%) with existing CVD, 49.3% (95% CI 28.8% to 69.8%) were on blood pressure (BP)-lowering medication, 4.7% (95% CI 0 to 10.4%) were on cholesterol-lowering medication, 24.6% (95% CI 9% to 40.3%) had increased exercise and 26.9% (95% CI 2.6% to 51.1%) attempted to quit smoking. Among the 7.6% (95% CI 6.2% to 8.9%) with a high global CHD risk (&gt;20% over 10 years), 29.5% (95% CI 19.5 to 39.5%) were on BP-lowering medication, 2.8% (95% CI 0 to 6.7%) were on cholesterol-lowering medication, 19.4% (95% CI 10.9% to 28%) had increased exercise and 24.8% (95% CI 15.8% to 33.8%) attempted to quit smoking. If confirmed drug therapies were provided to all individuals at high risk there would be a 28% reduction in cardiovascular events over 10 years at an approximate annual treatment cost of US$533 per event avoided. CONCLUSIONS: There are serious deficiencies in CVD prevention in rural areas of India. Addressing these with simple confirmed drug treatments could produce a large reduction in the future cardiovascular burden in India.
</p>
},
  year = {2011},
  journal = {Heart},
  volume = {97},
  edition = {2011/07/22},
  number = {17},
  pages = {1373-8},
  isbn = {1468-201X (Electronic)1355-6037 (Linking)},
  note = {Wood, AnnaPell, JillPatel, AnushkaNeal, BruceRaju, P KrishnamChow, Clara KResearch Support, Non-U.S. Gov'tEnglandHeart (British Cardiac Society)Heart. 2011 Sep;97(17):1373-8. Epub 2011 Jul 20.},
  language = {eng},
}