This theme focuses on the formulation and evaluation of needs-based, IT-enabled healthcare solutions for the management of common cardiometabolic diseases. Projects typically employ innovative software technologies and advanced data analytics of multi-source and multi-scale data, which are embedded into innovative models of care delivery.
Following initial development and validation, the effectiveness and safety of these solutions are assessed in randomised trials using both individual and cluster randomised designs. In addition to traditional summative evaluation of trial outcomes, detailed formative evaluation of processes during the course of the trial are conducted to help with both monitoring of the trial procedures at substantially lower costs of traditional monitoring models, as well as adaptation of interventions.
Current projects of this theme include the SUPPORT-HF study, which is a NIHR funded UK-based trial of a heart failure home monitoring and management system, and the SUPPORT-CVD study, which is a MRC/DFID/Wellcome Trust funded trial of a cardiovascular disease prevention programme in rural Iran with the use of digital technologies as well as a range of cardiovascular prevention polypills.