@article{16781, author = {}, title = {Norepinephrine: more of a neurohormone than a vasopressor}, abstract = {

Septic shock causes unpredictable cardiovascular responses through adrenoreceptor-mediated changes in cardiac function and vascular responsiveness. The use of norepinephrine should be regarded as neurohormonal augmentation therapy to defend decompensating haemodynamic function rather than as a rescue therapy to treat shock. Recent trials represent a perceptible change in clinical practice to preferentially use norepinephrine early in resuscitation to defend the mean arterial pressure and to use norepinephrine as a neurohormone rather than as a vasopressor.

}, year = {2010}, journal = {Critical Care}, volume = {14}, edition = {2010/09/24}, number = {5}, pages = {196}, isbn = {1466-609X (Electronic)1364-8535 (Linking)}, note = {Myburgh, JohnCommentEnglandCritical care (London, England)Crit Care. 2010;14(5):196. Epub 2010 Sep 20.}, language = {eng}, }